mri evaluation of liver iron concentration in patients with β-thalassemia major
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MRI Evaluation of Liver Iron Concentration in Patients with β-Thalassemia Major
β major is a hereditary anemia, characterized by a genetic deficiency in the synthesis of the β-globin chain (1). The main complication of the multiple blood transfusions to these patients is iron overload and the deposition of iron in various organs, such as the reticuloendothelial system, the liver, the heart and the endocrine glands (2). Chelators also have various side effects on multiple o...
full textCorrelation between Heart and Liver Iron Levels Measured by MRI T2* and Serum Ferritin in Patients with β-thalassemia Major
Background Transfusion-induced iron overload leads to many complications in patients with β-thalassemia major. This study aimed to compare the level of iron stored in the liver and heart measured by MRI T2 * with ferritin levels in these patients. Materials and Methods This study was done on 52 patients with β-thalassemia major aged 7 to 29 years. Serum ferritin level was checked and heart and ...
full textEVALUATION OF PULMONARY IRON OVER LOAD IN PATIENTS WITH Β-THALASSEMIA MAJOR USING SPIROMETRY
Background & Aims: Spirometry changes in thalassemic patients can be obstructive or restrictive and pulmonary dysfunction depends on age and body iron overload. In this study the effectiveness of lung spirometry in detecting iron overload in patients with β-thalassemia was investigated. Materials & Methods: This cross-sectional (descriptive-analytic) study investigated the spirometry test resu...
full textAssociation between serum ferritin and liver iron concentration with cardiac iron in pediatric thalassemia major patients
Background Recently, the ability of LIC (liver iron concentration) and serum ferritin in predicting myocardial iron overload (MIO) has been challenged by magnetic Resonance Imaging (MRI) monitoring which demonstrated no or weak correlation between serum ferritin or LIC and MIO. Anyway, the role of this traditional markers could result particularly useful in pediatric population, where MRI asses...
full textcorrelation between heart and liver iron levels measured by mri t2* and serum ferritin in patients with β-thalassemia major
background transfusion-induced iron overload leads to many complications in patients with β-thalassemia major. this study aimed to compare the level of iron stored in the liver and heart measured by mri t2 * with ferritin levels in these patients. materials and methods this study was done on 52 patients with β-thalassemia major aged 7 to 29 years. serum ferritin level was checked and heart and ...
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Journal title:
hepatitis monthlyجلد ۱۰، شماره ۲، صفحات ۱۴۹-۱۵۰
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